I've been scanning the Coworking Google Group and found an interesting thread about running coworking spaces as profit making businesses relative to non-profit enterprises. Given the idea behind coworking is very much about collaboration some people assume that a non-profit or cooperative structure might be preferred (and I started that way, too). However, there are many locations set up for profit, and many comments in this thread give reasons why it can make more sense to run the workspaces as a profit making business.
Here is a link to the article: Coworking as a business vs non-profit
Feel free to add your own thoughts here.
Marc.